Sensing small molecules with oligonucleotide aptamers

CORINNE, RAVELET and ERIC, DAUSSE and ERIC, PEYRIN and GUILLAUME, DURAND and JEAN-JACQUES, TOULME (2015) Sensing small molecules with oligonucleotide aptamers. In: Second International Conference on Advances in Bio-Informatics and Environmental Engineering - ICABEE 2015, 18 - 19 April, 2015, Rome, Italy.

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We developed biosensors in which the detection element is an oligonucleotide -an aptamer- obtained through a combinatorial process. We characterized aptamers specific for different biomarkers. They can be integrated into different devices, allowing their use either in a grafted format or in solution. We developped a multiplex assay signaling the presence of nucleoside derivatives by either surface plasmon resonance or fluorescence anisotropy.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: biosensor, oligonucleotide, aptamer, SPR, fluorescence, pollutant
Depositing User: Mr. John Steve
Date Deposited: 02 May 2019 11:17
Last Modified: 02 May 2019 11:17

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