New fully Metastasis inhibitor drug molecule: 1,8,8-trifluoro, 1 trifluoromethyl, 4a-(1,4,4-trifluorocyclohexyl) decalin A new novel drug intended to stop metastatic cancer

MUSTAFA, PEHLIVAN (2017) New fully Metastasis inhibitor drug molecule: 1,8,8-trifluoro, 1 trifluoromethyl, 4a-(1,4,4-trifluorocyclohexyl) decalin A new novel drug intended to stop metastatic cancer. In: Fifth International Conference on Advances in Bio-Informatics, Bio-Technology and Environmental Engineering - ABBE 2017, 02-03 September, 2017, Zurich, Switzerland.

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Abstract

This invention is about the discovery of a new drug molecule that will inhibit the enzyme Ty rosyl DNA Phosphodiesterase 1. T DP1 is a very important enzyme in terms of metastatic cancer treatment as it is involved in repairing damaged DNA of cancer cells. When Cancer cells (tumors) are damaged by Chemothera peutic anti cancer drugs, tyrosyl DNA Phosphodiesterase 1 is activated and repairs damaged cancer cells. As a result, cancer continues spreading within the body. If Tyrosyl DNA Phosphodiesterase 1 could be stopped doing that, cancer would stop spreading an d therefore the cancer Chemotherapy drugs will provide much better therapeutic effects that will lead to stopping cancer. For this reason, targeting Tyrosyl DNA Phosphodiesterase 1 has always been a target for Scientists who work on the discovery of new dr ug molecules. The purpose of this study is to introduce such a new drug molecule with computational results with the relevant data.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: — anticancer drug, cancer, computation, computational biology, computer modeling, drug discovery, metastasis, tumor metastasis, drug
Depositing User: Mr. John Steve
Date Deposited: 11 Mar 2019 08:32
Last Modified: 11 Mar 2019 08:32
URI: http://publications.theired.org/id/eprint/410

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